Первое время размер картриджей был ограничем объемом в 2 гигабайта, но сейчас достиг уже четырех. Носитель 3DS более емкий, чем например диски для GameCube (1,4G
.
4GB
Kingdom Hearts 3D: Dream Drop Distance (Square Enix)
Metal Gear Solid: Snake Eater 3D (Konami)
New Love Plus (Konami)
Resident Evil Revelations (Capcom)
2GB
Blazblue Continuum Shift II (Aksys Games)
Dead or Alive Dimensions (Koei Tecmo)
Doctor Lautrec and the Forgotten Knights (Konami)
Monster Hunter Tri G (Capcom)
Samurai Warriors Chronicles (Koei Tecmo)
Super Street Fighter IV: 3D Edition (Capcom)
Tales of the Abyss (Bandai Namco)
Thor: God of Thunder (Sega)
Tom Clancy's Splinter Cell 3D (Ubisoft)
1GB
Captain America: Super Soldier (Sega)
Madden NFL Football (Electronic Arts)
Mario Kart 7 (Nintendo)
Pro Evolution Soccer 2011 3D (Konami)
Resident Evil: The Mercenaries 3D (Capcom)
Ridge Racer 3D (Bandai Namco)
Sonic Generations (Sega)
Star Fox 64 3D (Nintendo)
512MB
Asphalt 3D (Ubisoft)
bit.trip Saga (Aksys Games)
Cave Story 3D (Nippon Ichi Soft)
Driver Renegade 3D (Ubisoft)
Harvest Moon 3D: The Tale of Two Towns (Natsume)
LEGO Pirates of the Caribbean: The Video Game (Disney)
LEGO Star Wars III: The Clone Wars (LucasArts)
Nintendogs + Cats (Nintendo)
Pokemon Rumble Blast (Nintendo)
Shinobi (Sega)
Super Mario 3D Land (Nintendo)
The Legend of Zelda: Ocarina of Time 3D (Nintendo)
The Sims 3 (Electronic Arts)
256MB
Dream Trigger 3D (Bandai Namco)
Green Lantern: Rise of the Manhunters (WB Games)
Rayman 3D (Ubisoft)
SpongeBob SquigglePants (THQ)
Steel Diver (Nintendo)
Super Monkey Ball 3D (Sega)
Tetris Axis (Nintendo)
Tom Clancy's Ghost Recon: Shadow Wars (Ubisoft)
128MB
Bust-A-Move Universe (Square Enix)
Cubic Ninja (Ubisoft)
PilotWings Resort (Nintendo)
Стоит отметить, что под конец жизненного цикла игры для оригинальной DS достигли отметки в 512MB.